Quality Manufacturer Supply High Purity 99% Methyl 3-amino-4-hydroxybenzoate 536-25-4 with Reasonable Price
- Molecular Formula: C8H9NO3
- Molecular Weight: 167.164
- Vapor Pressure: 0.000111mmHg at 25°C
- Melting Point: 141-143 °C
- Refractive Index: 1.605
- Boiling Point: 326.801 °C at 760 mmHg
- PKA: 8.15±0.18(Predicted)
- Flash Point: 151.444 °C
- PSA： 72.55000
- Density: 1.305 g/cm3
- LogP: 1.34220
Methyl 3-amino-4-hydroxybenzoate(Cas 536-25-4) Usage
InChI:InChI=1/C8H9NO3/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4,10H,9H2,1H3
536-25-4 Relevant articles
Synthesis and biological activities of some Novel 2-Amino-(5 or 7-Substituted- 2-Oxoindolin-3-Ylidene) Benzoxazole-5-Carbohydrazide derivatives
Rajyalakshmi,Reddy, A. Rama Narsimha,Sarangapani
, p. 625 - 632 (2012)
A series of 2-amino-(5 or 7-substituted-...
Sulfatase-cleavable linkers for antibody-drug conjugates
Bargh, Jonathan D.,Carroll, Jason S.,Isidro-Llobet, Albert,Omarjee, Soleilmane,Spring, David R.,Walsh, Stephen J.
, p. 2375 - 2380 (2020)
Antibody-drug conjugates (ADCs) are a cl...
Heterocyclic substituted biphenyl compound as well as preparation method and application thereof
-
Paragraph 0296; 0298; 0301-0302, (2021/08/28)
The invention discloses a heterocyclic s...
Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors
Jaikhan, Pattaporn,Buranrat, Benjaporn,Itoh, Yukihiro,Chotitumnavee, Jiranan,Kurohara, Takashi,Suzuki, Takayoshi
supporting information, p. 1173 - 1176 (2019/03/29)
Fe(II)/α-ketoglutarate-dependent lysine ...
Synthesis, Structure Revision, and Cytotoxicity of Nocarbenzoxazole G
Kim, Taejung,Lee, Sin-Ae,Noh, Taesub,Choi, Pilju,Choi, Seon-Jun,Song, Bong Geun,Kim, Youngseok,Park, Young-Tae,Huh, Gyuwon,Kim, Young-Joo,Ham, Jungyeob
, p. 1325 - 1330 (2019/05/04)
The total synthesis of nocarbenzoxazoles...
536-25-4 Process route
-
-
67-56-1
methanol
-
-
1571-72-8
3-amino-4-hydroxybenzoic acid
-
-
536-25-4
methyl 3-amino-4-hydroxybenzoate
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
for 24h;
Reflux;
|
100%
|
|
With
acetyl chloride;
for 12h;
Heating;
|
99%
|
|
With
acetyl chloride;
at 0 - 20 ℃;
for 12h;
Heating / reflux;
|
99%
|
|
With
hydrogenchloride;
at 0 - 20 ℃;
for 24h;
|
98%
|
|
With
hydrogenchloride;
In
water;
for 22h;
Reflux;
|
97%
|
|
With
sulfuryl dichloride;
at 5 - 65 ℃;
for 8h;
Large scale reaction;
|
95%
|
|
With
sulfuric acid;
at 0 - 70 ℃;
for 8h;
|
93%
|
|
With
acetyl chloride;
at 0 ℃;
Reflux;
|
93.1%
|
|
With
hydrogenchloride;
for 4h;
Heating;
|
76.5%
|
|
With
chloro-trimethyl-silane;
at 55 ℃;
for 48h;
|
57%
|
|
With
sulfuric acid;
for 24h;
Inert atmosphere;
Reflux;
|
47%
|
|
With
hydrogenchloride;
|
|
|
With
sulfuric acid;
for 24h;
Heating;
|
|
|
With
sulfuric acid;
Heating;
|
|
|
methanol; 3-amino-4-hydroxybenzoic acid;
With
acetyl chloride;
at 0 - 20 ℃;
for 18h;
With
water; sodium hydrogencarbonate;
at 0 ℃;
|
|
|
With
hydrogenchloride; toluene-4-sulfonic acid;
for 12h;
Reflux;
|
-
-
1571-72-8
3-amino-4-hydroxybenzoic acid
-
-
536-25-4
methyl 3-amino-4-hydroxybenzoate
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
In
methanol;
at 65 ℃;
for 6h;
|
81%
|
|
With
methanol; sulfuric acid;
|
536-25-4 Upstream products
-
99-42-3
methyl (4-hydroxy-3-nitro)benzoate
-
67-56-1
methanol
-
1571-72-8
3-amino-4-hydroxybenzoic acid
-
91-66-7
N,N-diethylaniline
536-25-4 Downstream products
-
136663-21-3
methyl 2-methyl-1,3-benzoxazole-5-carboxylate
-
126360-59-6
methyl 3-(N-acetyl)amino-4-hydroxybenzoate
-
82525-66-4
3-(2-chloro-acetylamino)-4-hydroxy-benzoic acid methyl ester
-
82525-67-5
4-hydroxy-3-{[N -(2-hydroxy-5-methoxycarbonyl-phenyl)-glycyl]-amino}-benzoic acid methyl ester
