2,5-DIMETHYL-1-PHENYLPYRROLE-3-CARBOXALDEHYDE

  • CAS No.: 83-18-1
  • Purity: 99%
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Manufacturer Supply Best Quality 2,5-DIMETHYL-1-PHENYLPYRROLE-3-CARBOXALDEHYDE 83-18-1 with Efficient Transportation

  • Molecular Formula: C13H13 N O
  • Molecular Weight: 199.252
  • Vapor Pressure: 6E-05mmHg at 25°C 
  • Melting Point: 89-90°C 
  • Boiling Point: 345.8°C at 760 mmHg 
  • PKA: -5.56±0.70(Predicted) 
  • Flash Point: 163°C 
  • PSA: 22.00000 
  • Density: 1.04 
  • LogP: 2.90660 

2,5-DIMETHYL-1-PHENYLPYRROLE-3-CARBOXALDEHYDE(Cas 83-18-1) Usage

InChI:InChI=1/C13H19NO/c1-10-8-12(9-15)11(2)14(10)13-6-4-3-5-7-13/h8-9,13H,3-7H2,1-2H3

83-18-1 Relevant articles

Synthesis, structure and in vitro anti-trypanosomal activity of non-toxic arylpyrrole-based chalcone derivatives

Hoppe, Heinrich C.,Isaacs, Michelle,Khanye, Setshaba D.,Kruger, Cuan,Oderinlo, Ogunyemi O.,Smith, Vincent J.,Veale, Clinton G. L.,Zulu, Ayanda I.

supporting information, (2020/04/10)

With an intention of identifying chalcon...

ANDROGEN RECEPTOR ANTAGONISTS

-

Paragraph 0333-0335, (2019/08/26)

Compounds that inhibit the androgen rece...

Direct Synthesis of Pyrroles via Heterogeneous Catalytic Condensation of Anilines with Bioderived Furans

Tao, Lei,Wang, Zi-Jian,Yan, Tian-Hao,Liu, Yong-Mei,He, He-Yong,Cao, Yong

, p. 959 - 964 (2017/08/09)

Given the wide applications of pyrroles ...

Discovery and optimisation studies of antimalarial phenotypic hits

Mital, Alka,Murugesan, Dinakaran,Kaiser, Marcel,Yeates, Clive,Gilbert, Ian H.

supporting information, p. 530 - 538 (2015/10/12)

There is an urgent need for the developm...

83-18-1 Process route

2,5-dimethyl-1-phenyl-1H-pyrrole
83-24-9

2,5-dimethyl-1-phenyl-1H-pyrrole

N,N-dimethyl-formamide
68-12-2,33513-42-7

N,N-dimethyl-formamide

2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde
83-18-1

2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde

Conditions
Conditions Yield
With trichlorophosphate; at 110 ℃; for 6h;
91%
With trichlorophosphate; at 100 ℃; for 3h; Cooling with ice; Inert atmosphere;
90%
N,N-dimethyl-formamide; With trichlorophosphate; at 0 ℃; for 0.333333h; Inert atmosphere;
2,5-dimethyl-1-phenyl-1H-pyrrole; at 60 ℃; for 4h; Inert atmosphere;
84%
With trichlorophosphate; Yield given. Multistep reaction; 1) 15 min, r.t., 2) 3 h, 100 deg C;
2,5-dimethyl-1-phenyl-1H-pyrrole; N,N-dimethyl-formamide; With trichlorophosphate; In toluene; at 110 ℃; for 6h;
With water; sodium acetate; In toluene; at 20 ℃; for 0.333333h;
With trichlorophosphate; at 0 - 60 ℃; for 3h;
With trichlorophosphate; at 0 - 100 ℃; for 3h;
N-(3′-methylphenyl)-2,5-dimethylpyrrole
32570-10-8

N-(3′-methylphenyl)-2,5-dimethylpyrrole

2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde
83-18-1

2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde

Conditions
Conditions Yield
With trichlorophosphate; In N,N-dimethyl-formamide; at 110 ℃;

83-18-1 Upstream products

  • 83-24-9
    83-24-9

    2,5-dimethyl-1-phenyl-1H-pyrrole

  • 77287-34-4
    77287-34-4

    formamide

  • 68-12-2
    68-12-2

    N,N-dimethyl-formamide

  • 110-13-4
    110-13-4

    2,5-hexanedione

83-18-1 Downstream products

  • 115121-44-3
    115121-44-3

    1-ethyl-2-[2-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-vinyl]-6,7-dihydro-4H -pyrano[4,3-d ]thiazolium; iodide

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