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1.What is the morpholin-3-one ?
3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.
Used in Pharmaceutical Industry:
Morpholin-3-one is used as a pharmacological intermediate for the development of potential anti-cancer drugs. Its derivatives have been found to effectively cause cell cycle arrest at the G1 phase, increase the levels of P53 and Fas, and induce apoptosis in lung cancer cells, making it a promising candidate for elucidating the molecular mechanisms of lung cancer cell apoptosis.
Used in Cardiovascular Disease Management:
Morpholin-3-one derivatives have demonstrated utility in the prevention and treatment of arteriosclerosis and hypertriglyceridemia, contributing to the management of cardiovascular diseases by targeting specific biological pathways and offering therapeutic benefits.
2.What is the CAS number for morpholin-3-one ?
The CAS number of morpholin-3-one is 109-11-5.
More information of morpholin-3-one 109-11-5 are:
|
CAS?Number |
109-11-5 |
|
Density |
1.122 g/cm3 |
|
Melting Point |
104-106℃ |
|
Boiling Point |
313 °C at 760 mmHg |
|
Flash Point |
143.1 °C |
|
Vapor Pressure |
0.000512mmHg at 25°C |
|
Refractive Index |
1.435 |
|
HS CODE |
29349990 |
|
PSA |
38.33000 |
|
LogP |
-0.53840 |
|
Pka |
14.37±0.20(Predicted) |
3.What is the molecular formula of morpholin-3-one ?
The chemical formula of?morpholin-3-one is C4H7NO2 which containing 4 Carbon atoms,7 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of morpholin-3-one is 101.105
4.What is morpholin-3-one(109-11-5)used for?
3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.
InChI:InChI=1/C4H7NO2/c6-4-3-7-2-1-5-4/h1-3H2,(H,5,6)
Relevant articles related to morpholin-3-one:
|
Article |
Source |
|
In vitro inhibition studies of phytoene desaturase by bleaching ketomorpholine derivatives |
Sandmann, Gerhard,Mitchell, Glynn , p. 138 - 141 (2001) |
|
Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides |
Jin, Xiongjie,Kataoka, Kengo,Yatabe, Takafumi,Yamaguchi, Kazuya,Mizuno, Noritaka supporting information, p. 7212 - 7217 (2016/07/06) |
5.Excellent chemical plant bulk supply morpholin-3-one 109-11-5
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