N-Dodecanoyl-L-serine

  • CAS No.: 14379-56-7
  • Purity: 99%
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Chinese Manufacturer supply N-Dodecanoyl-L-serine 14379-56-7 in stock with high standard

  • Molecular Formula: C15H29NO4
  • Molecular Weight: 287.4
  • Vapor Pressure: 0mmHg at 25°C 
  • Refractive Index: 1.482 
  • Boiling Point: 500.116 °C at 760 mmHg 
  • Flash Point: 256.261 °C 
  • PSA: 86.63000 
  • Density: 1.047g/cm3 
  • LogP: 2.85990 

N-Dodecanoyl-L-serine(Cas 14379-56-7) Usage

General Description

N-Dodecanoyl-L-serine is a chemical compound that falls under the category of serine derivatives. It consists of a dodecanoyl chain attached to the amino acid serine. N-Dodecanoyl-L-serine has potential applications in the fields of cosmetics and pharmaceuticals due to its surfactant properties and its ability to act as a anti-irritant and anti-inflammatory agent. Additionally, N-Dodecanoyl-L-serine has shown promise in skin care products and topical treatments for various dermatological conditions. However, further research is required to fully understand its potential uses and effects.

InChI:InChI=1/C15H29NO4/c1-2-3-4-5-6-7-8-9-10-11-14(18)16-13(12-17)15(19)20/h13,17H,2-12H2,1H3,(H,16,18)(H,19,20)/t13-/m0/s1

14379-56-7 Relevant articles

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Inoue,T. et al.

, p. 719 - 723 (1976)

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Synthetic ceramide analogues as skin permeation enhancers: Structure-Activity relationships

Vavrova, Katerina,Hrabalek, Alexandr,Dolezal, Pavel,Samalova, Lucie,Palat, Karel,Zbytovska, Jarmila,Holas, Tomas,Klimentova, Jana

, p. 5381 - 5390 (2003)

The study presents new information about...

Hydrogen-bonding networks involving water in amphiphilic N-dodecanoyl-L-serine monohydrate

Schade,Fuhrhop,Hubert,Weber,Luger

, p. 1070 - 1073 (1997)

The amphiphilic title compound, C15H29NO...

The relationship between the structure and properties of amino acid surfactants based on glycine and serine

Qiao, Weihong,Qiao, Yangyang

, p. 821 - 828 (2013/11/06)

Two series of surfactants based on glyci...

The effect of unsaturation on the formation of self-assembled gels from fatty acid L-serine amides and their cytotoxicity towards caco-2 cancer cells

Lim, Li Yun Grace,Su, Yingying,Braet, Filip,Thordarson, Pall

scheme or table, p. 653 - 656 (2010/01/16)

A series of saturated and unsaturated fa...

A novel acylase from Streptomyces mobaraensis that efficiently catalyzes hydrolysis/synthesis of capsaicins as well as N-acyl-L-amino acids and N-acyl-peptides

Koreishi, Mayuko,Zhang, Demin,Imanaka, Hiroyuki,Imamura, Koreyoshi,Adachi, Shuji,Matsuno, Ryuichi,Nakanishi, Kazuhiro

, p. 72 - 78 (2007/10/03)

A novel enzyme that catalyzes efficient ...

CHIRAL SURFACTANT AND METHOD FOR USING THE SAME IN CHIRAL SEPARATION

-

Page/Page column 14, (2010/02/11)

PROBLEM TO BE SOLVED: To provide a metho...

14379-56-7 Process route

N-succinimidyl laurate
14565-47-0

N-succinimidyl laurate

L-serin
56-45-1,83245-15-2

L-serin

N-Lauroylserine
14379-56-7

N-Lauroylserine

Conditions
Conditions Yield
With sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 20 ℃; for 16h;
93%
70%
With sodium hydrogencarbonate; In tetrahydrofuran; water; Inert atmosphere;
n-dodecanoyl chloride
112-16-3

n-dodecanoyl chloride

N-Lauroylserine
14379-56-7

N-Lauroylserine

Conditions
Conditions Yield
Sasrin resin-bound Fmoc-L-Ser(t-Bu); With piperidine; In N,N-dimethyl-formamide; at 20 ℃;
n-dodecanoyl chloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h;
With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;
94%

14379-56-7 Upstream products

  • 112-16-3
    112-16-3

    n-dodecanoyl chloride

  • 56-45-1
    56-45-1

    L-serin

  • 14565-47-0
    14565-47-0

    N-succinimidyl laurate

  • 143-07-7
    143-07-7

    lauric acid

14379-56-7 Downstream products

  • 56-45-1
    56-45-1

    L-serin

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